KEY TAKEAWAYS
- Plume integrates native USDC and Cross-Chain Transfer Protocol V2 to enhance cross-chain transfers and access to USDC.
- Since its mainnet launch, Plume’s Total Value Locked has surged by 441%, hosting over 200 applications.
- Native USDC integration aims to unlock new use cases in RWAfi, DeFi, and social applications, facilitating fast settlements and cross-chain transfers.
- Plume’s integration with Circle Mint enhances institutional access, enabling secure USDC movement with 1:1 capital efficiency.
Plume, a blockchain designed for real-world asset finance (RWAfi) and decentralized finance (DeFi), is set to enhance its ecosystem with the integration of native USDC and Cross-Chain Transfer Protocol (CCTP) V2. This development aims to provide seamless cross-chain transfers and access to the world’s largest regulated stablecoin, USDC.
Since the launch of Plume’s Genesis mainnet on June 5, 2025, the platform has seen significant growth. The Total Value Locked (TVL) on Plume has increased by over 441%, rising from $44 million to $238 million as of September 4, 2025. The ecosystem now hosts over 200 applications and protocols.
Native USDC Integration and Its Impact
The introduction of native USDC on Plume is expected to unlock new use cases across various sectors, including RWAfi, DeFi, and social applications. Native USDC will serve as a foundational building block for tokenizing real-world assets, enabling fast settlement and seamless cross-chain transfers.
Currently, Plume supports Bridged USDC (USDC.e) via the Stargate bridge from Ethereum. The network plans to transition from bridged to native USDC over time, although the Stargate bridge will continue to operate without immediate changes. Bridged USDC will remain labeled as “USDC.e” in block explorers and app interfaces.
Enhancing Institutional Access and Efficiency
With the integration of native USDC, Plume aims to enhance institutional on/off-ramps through Circle Mint, allowing eligible users to redeem USDC directly. This integration is designed to facilitate secure movement of USDC between Plume and supported blockchains with 1:1 capital efficiency.
Developers on Plume can leverage native USDC to build applications with seamless cross-chain onboarding, swaps, purchases, and treasury rebalancing. The integration is expected to bolster the development of automated market makers (AMMs) and other financial primitives within the DeFi space.
More details about the integration of native USDC and CCTP V2 on Plume can be found here.
Why This Matters: Impact, Industry Trends & Expert Insights
Plume Blockchain’s integration of native USDC and CCTP V2 marks a significant development in enhancing cross-chain financial operations and increasing access to regulated stablecoins within the DeFi ecosystem.
Recent industry reports indicate that tokenization of real-world assets (RWAs) is a hallmark trend, with a rapidly growing market valued at over $24 billion in mid-2025. This aligns with Plume’s strategy to leverage native USDC for tokenizing real-world assets, facilitating faster settlements and seamless transfers.
As per insights from industry experts, USDC is regarded as a crucial stablecoin in the DeFi ecosystem in 2025, widely used for liquidity provision, lending, and yield farming. This supports Plume’s integration efforts, as USDC’s programmability is expected to drive new use cases and enhance institutional access.
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